• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    METHOD OF MANUFACTURING THE CASE OF CAPSULES) by immersing a pin with an annular groove on it into a gelatinous mass above the constriction, removing the pin from the mass, removing the mass of the capsule body from the immersion pin and then cutting the body to a predetermined length, and This also means that, in order to eliminate the deformation of the walls when the housing is connected to the roof, the cutting is performed in the zone of the smallest diameter of the annular groove.
    公开号:SU1127524A3
    申请号:SU782619148
    申请日:1978-05-19
    公开日:1984-11-30
    发明作者:Ульрих Боденманн Ханс；Ван Херле Лу；Мартенс Винанд
    申请人:Капсугел Аг (Фирма)；
    IPC主号:
    专利说明:

    1
    This invention relates to the pharmaceutical industry and relates to a method for producing detachable capsules for medicinal substances.
    A known method of making 5 capsule bodies is by immersing a pin with an annular groove made on it into a gelatinous mass above the constriction, removing the pin from the mass, removing the capsule body mass from the immersion pin followed by cutting the body by a given length il.
    However, when the body of the capsule is connected to the lid, there is an impact of its edges, which leads to deformation of the walls. I
    The purpose of the invention is to eliminate the deformation of the walls when connecting the building-2Q sa, with a cover.
     The goal is achieved in that according to the method of manufacturing the capsule body by immersing the pin with an annular groove 25 on it into the gelatinous mass above the night, removing the pin from the mass, removing the mass of the capsule body from the immersion pin followed by cutting, By cutting the housing to a predetermined length, cutting is performed in the zone of the smallest diameter of the annular groove.
    The method is carried out by following, Braz.
    A pin is submerged in a bath filled with hardened liquid, for example gelatin, the lower end of which is rounded so that the liquid will cover a 40-second annular recess on it.
    After removing the immersion pin from the bath, a layer of solidified liquid remains on it. In order to maintain a uniform layer thickness, when 45 the liquid has not yet hardened and is fluid, it is rotated around the transverse axis so that its lower end is alternately at the top and bottom. 50
    After the mass has hardened, the immersion pin is installed in a cartridge consisting of two or more parts, which move each other towards each other so that they grip the hardened layer radially. After that, the immersion pin is pushed upward from the cartridge, as a result of which the layer of solidified mass remains in the cartridge in the form of a long body with a constriction.
    Depending on the elasticity of the body material, various sizes can be used. If the diameter of the immersion pin is 6.7 mm, then the recess is an axial length of 1.5 mm and a depth of approximately 0.09 mm. The axial width of the recess should be about 10–20 times greater than its depth.
    The end surface of the cartridge is flat and is on the same straight line as the constriction. After the pin has been moved, the body is cut with a knife at the point of constriction, the cartridge and the body being rotated around the longitudinal axis of the pin.
    By radially extending the parts of the cartridge, the finished body is released, which has a reduced diameter in the open end region.
    FIG. 1 to 5 schematically depict various stages in the implementation of the proposed method for manufacturing a hull hull body.
    Bath 1 (Fig. 1) is filled with a gelatinous mass. Submersible pin 2 is rounded from the bottom, and on the opposite side has an annular recess 3 around the circumference.
    The pin 2 is immersed in the bath 1 so that the gelatinous mass covers the pin above the recess 3.
    After viimani of the submersible pin of the short-circuit bath, a layer of solidified mass 4 remains on it (Fig. 2).
    After the mass has hardened, the immersion pin is installed in the cartridge 5, consisting of two or more parts 6 and 7, which is moved towards WPyr DRZtu so that they seize the hardened layer radially (Fig. 5). After that, the immersion pin is pushed up from the cartridge (Fig. 4), as a result of which the layer of solidified mass remains in the cartridge as a long body 8 with a narrowing 9. After the pin is extended, the body is cut using a knife 10. By means of radial expansion of the parts of the cartridge free the finished body 11 . (Fig. 5), which has a reduced diameter in the area of the open end 12.
    The resulting capsules are suitable for filling them with powdered or liquid substances. At the same time, lightening3, 11275244
    The connection of the housing with the cap is eliminated, the process is stopped, the deformation of their walls, the filling machine is eliminated, and the disassembly is eliminated during an uninterrupted technological operation of the walls of the cap or housing.
    FIG. 2
    T2
    If
    权利要求:
    Claims (1)
    [1]
    METHOD FOR MAKING A CAPSULE CASE by immersing a pin with an annular groove made on it in a gelatinous mass above the constriction, removing the pin from the mass, removing the capsule body formed after hardening from the immersion pin, and then cutting the body to a predetermined length, which can be removed that, in order to eliminate the deformation of the walls when connecting the housing to the cover, cutting is performed in the zone of the smallest diameter of the annular groove.
    SUn., 1127524>
    Figure 1.
    ί * 127524 2
    类似技术:
    公开号 | 公开日 | 专利标题
    SU1127524A3|1984-11-30|Method of manufacturing capsule case
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    JPS5583560A|1980-06-24|Abrasion method
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    JPS6161672A|1986-03-29|Coating method
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    同族专利:
    公开号 | 公开日
    ES242664Y|1980-04-01|
    EG14108A|1983-03-31|
    GR64534B|1980-04-10|
    RO84527A2|1984-06-21|
    FI68969C|1985-12-10|
    DK199878A|1978-11-21|
    DE2722806C2|1984-12-13|
    ES469989A1|1979-09-16|
    JPS53145908A|1978-12-19|
    NL181904C|1987-12-01|
    SE442166B|1985-12-09|
    NO146456B|1982-06-28|
    AR221842A1|1981-03-31|
    CH624900A5|1981-08-31|
    AU521515B2|1982-04-08|
    AU3626278A|1979-11-22|
    IE46974B1|1983-11-16|
    ATA365978A|1981-01-15|
    FR2390947B1|1980-04-04|
    IE781008L|1978-11-20|
    BR7803155A|1979-01-09|
    NL7805393A|1978-11-22|
    YU150182A|1989-02-28|
    FI68969B|1985-08-30|
    GB1597303A|1981-09-03|
    ES242665Y|1980-04-01|
    NL181904B|1987-07-01|
    DE2722806A1|1978-11-23|
    PT68059B|1979-10-26|
    NO781743L|1978-11-21|
    BG31064A3|1981-10-15|
    TR19872A|1980-04-03|
    RO84527B1|1984-08-30|
    PL206968A1|1979-02-12|
    IT7849462D0|1978-05-19|
    JPS6323172B2|1988-05-16|
    PT68059A|1978-06-01|
    ES242664U|1979-10-16|
    SE7805760L|1978-11-21|
    FI781593A|1978-11-21|
    DK150812B|1987-06-29|
    CA1100873A|1981-05-12|
    AT363605B|1981-08-25|
    ES242665U|1979-10-16|
    DK150812C|1987-12-21|
    ZA782874B|1979-06-27|
    CS205123B2|1981-04-30|
    PL114266B1|1981-01-31|
    MX5217E|1983-04-25|
    YU121678A|1983-02-28|
    NO146456C|1982-10-06|
    BE867233A|1978-09-18|
    YU45543B|1992-05-28|
    US4247006A|1981-01-27|
    HU178486B|1982-05-28|
    FR2390947A1|1978-12-15|
    DD135469A5|1979-05-09|
    IT1103484B|1985-10-14|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US525845A|1894-09-11|Riley p |
    BE655413A|
    US525844A|1894-09-11|Eiley p |
    AT10823B|1900-11-19|1903-02-25|Otto Krahl|
    US2936493A|1955-06-16|1960-05-17|Scherer Corp R P|Method of making plastic capsules|
    US3285408A|1964-10-16|1966-11-15|Lilly Co Eli|Capsule with integral locking band|
    US3258115A|1965-05-12|1966-06-28|Scherer Corp R P|Two-piece hard gelatin capsule|
    US3399803A|1966-10-11|1968-09-03|Parke Davis & Co|Self-locking medicament capsule|
    US3653500A|1969-07-11|1972-04-04|Lilly Co Eli|Filled capsules|
    US3664495A|1970-12-21|1972-05-23|Parke Davis & Co|Locking capsule|
    US3927195A|1974-01-31|1975-12-16|Lilly Industries Ltd|Production of capsules|
    US4040536A|1975-05-05|1977-08-09|R. P. Scherer Corporation|Locking hard gelatin capsule|
    US4138013A|1976-08-27|1979-02-06|Parke, Davis & Company|Enteric capsules|DE3371865D1|1982-10-29|1987-07-09|Warner Lambert Co|Tamper-resistant capsules|
    US4667498A|1984-06-29|1987-05-26|Sauter Manufacturing Corp.|Method and apparatus of making gelatine capsule forming pins having a rounded locking groove|
    US4758149A|1984-06-29|1988-07-19|Sauter Manufacturing Co.|Capsule forming pin having a burnish-hardened surface|
    DE3907973A1|1989-03-11|1990-09-13|Merck Patent Gmbh|DRYER TABLET|
    US5261211A|1991-03-28|1993-11-16|Huntamaki Oy|Method for manufacturing of subcutaneous capsules|
    AT147255T|1991-03-28|1997-01-15|Leiras Oy|METHOD FOR PRODUCING SUBCUTANEOUS CAPSULES|
    DE69120970T2|1991-03-28|1997-02-20|Leiras Oy|DEVICE FOR PRODUCING SUBCUTANEOUS CAPSULES|
    DE69221300D1|1991-05-31|1997-09-04|Gs Technologies Inc|METHOD AND DEVICE FOR PRODUCING PHARMACEUTICAL CELLULOSE CAPSULES|
    US5698155A|1991-05-31|1997-12-16|Gs Technologies, Inc.|Method for the manufacture of pharmaceutical cellulose capsules|
    US5769267A|1995-11-09|1998-06-23|Warner-Lambert Company|Container|
    US5993185A|1996-03-21|1999-11-30|Farmacapsulas S.A.|Deck plate assemblies for forming capsules|
    US5945136A|1997-04-03|1999-08-31|Technophar Equipment & Service Limited|Heating elevator for capsule making machine|
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    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    DE2722806A|DE2722806C2|1977-05-20|1977-05-20|Capsule body for a push-fit capsule for drugs or other substances to be packaged in portions, as well as a process for its production|
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